Effects of long-term salicylate administration on synaptic ultrastructure and metabolic activity in the rat CNS

Tinnitus is associated with neural hyperactivity in the central nervous system (CNS). Salicylate is a well-known ototoxic drug, and we induced tinnitus in rats using a model of long-term salicylate administration. The gap pre-pulse inhibition of acoustic startle test was used to infer tinnitus perce...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Yi, Bin, Hu, Shousen, Zuo, Chuantao, Jiao, Fangyang, Lv, Jingrong, Chen, Dongye, Ma, Yufei, Chen, Jianyong, Mei, Ling, Wang, Xueling, Huang, Zhiwu, Wu, Hao
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4828705/
https://ncbi.nlm.nih.gov/pubmed/27068004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24428
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