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Sigma1 receptors inhibit store-operated Ca(2+) entry by attenuating coupling of STIM1 to Orai1
Sigma1 receptors (σ1Rs) are expressed widely; they bind diverse ligands, including psychotropic drugs and steroids, regulate many ion channels, and are implicated in cancer and addiction. It is not known how σ1Rs exert such varied effects. We demonstrate that σ1Rs inhibit store-operated Ca(2+) entry...
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| Publicado en: | J Cell Biol |
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| Autores principales: | , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
The Rockefeller University Press
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4828687/ https://ncbi.nlm.nih.gov/pubmed/27069021 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201506022 |
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