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RUNX2 Mutation Impairs 1α,25-Dihydroxyvitamin D(3) mediated Osteoclastogenesis in Dental Follicle Cells
Cleidocranial dysplasia (CCD), a skeletal disorder characterized by delayed permanent tooth eruption and other dental abnormalities, is caused by heterozygous RUNX2 mutations. As an osteoblast-specific transcription factor, RUNX2 plays a role in bone remodeling, tooth formation and tooth eruption. T...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4828645/ https://ncbi.nlm.nih.gov/pubmed/27068678 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24225 |
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