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HAPCAD: An open-source tool to detect PCR crossovers in next-generation sequencing generated HLA data

Next-generation sequencing (NGS) based HLA genotyping can generate PCR artifacts corresponding to IMGT/HLA Database alleles, for which multiple examples have been observed, including sequence corresponding to the HLA-DRB1*03:42 allele. Repeat genotyping of 131 samples, previously genotyped as DRB1*0...

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Detalhes bibliográficos
Publicado no:Hum Immunol
Main Authors: McDevitt, Shana L., Bredeson, Jessen V., Roy, Scott W., Lane, Julie A., Noble, Janelle A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4828336/
https://ncbi.nlm.nih.gov/pubmed/26802209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.humimm.2016.01.013
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