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HAPCAD: An open-source tool to detect PCR crossovers in next-generation sequencing generated HLA data
Next-generation sequencing (NGS) based HLA genotyping can generate PCR artifacts corresponding to IMGT/HLA Database alleles, for which multiple examples have been observed, including sequence corresponding to the HLA-DRB1*03:42 allele. Repeat genotyping of 131 samples, previously genotyped as DRB1*0...
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Publicado no: | Hum Immunol |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4828336/ https://ncbi.nlm.nih.gov/pubmed/26802209 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.humimm.2016.01.013 |
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