Intracerebroventricular administration of TNF-like weak inducer of apoptosis induces depression-like behavior and cognitive dysfunction in non-autoimmune mice

Fn14, the sole known signaling receptor for the TNF family member TWEAK, is inducibly expressed in the central nervous system (CNS) in endothelial cells, astrocytes, microglia, and neurons. There is increasing recognition of the importance of the TWEAK/Fn14 pathway in autoimmune neurologic condition...

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Bibliographic Details
Published in:Brain Behav Immun
Main Authors: Wen, Jing, Chen, Chris, Stock, Ariel, Doerner, Jessica, Gulinello, Maria, Putterman, Chaim
Format: Artigo
Language:Inglês
Published: 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4828298/
https://ncbi.nlm.nih.gov/pubmed/26721417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2015.12.017
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