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CXCL13 promotes isotype-switched B cell accumulation to the central nervous system during viral encephalomyelitis

Elevated CXCL13 within the central nervous system (CNS) correlates with humoral responses in several neuroinflammatory diseases, yet its role is controversial. During coronavirus encephalomyelitis CXCL13 deficiency impaired CNS accumulation of memory B cells and antibody-secreting cells (ASC) but no...

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Bibliographische Detailangaben
Veröffentlicht in:Brain Behav Immun
Hauptverfasser: Phares, Timothy W., DiSano, Krista D., Stohlman, Stephen A., Segal, Benjamin M., Bergmann, Cornelia C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier Inc. Published by Elsevier Inc. 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4828287/
https://ncbi.nlm.nih.gov/pubmed/26795429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2016.01.016
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