Radiation-induced changes in DNA methylation of repetitive elements in the mouse heart

DNA methylation is a key epigenetic mechanism, needed for proper control over the expression of genetic information and silencing of repetitive elements. Exposure to ionizing radiation, aside from its strong genotoxic potential, may also affect the methylation of DNA, within the repetitive elements,...

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Udgivet i:Mutat Res
Main Authors: Koturbash, Igor, Miousse, Isabelle R., Sridharan, Vijayalakshmi, Nzabarushimana, Etienne, Skinner, Charles M., Melnyk, Stepan B., Pavliv, Oleksandra, Hauer-Jensen, Martin, Nelson, Gregory A., Boerma, Marjan
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4828271/
https://ncbi.nlm.nih.gov/pubmed/26963372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrfmmm.2016.02.009
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