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Metformin Prevents Hepatocellular Carcinoma Development by Suppressing Hepatic Progenitor Cell Activation in a Rat Model of Cirrhosis

BACKGROUND: Hepatocellular carcinoma (HCC) associated mortality is increasing at an alarming rate and there is a readily identifiable cohort of at risk patients with cirrhosis, viral hepatitis, non-alcoholic fatty liver disease, and diabetes. These patients are candidates for chemoprevention. Metfor...

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Detalhes bibliográficos
Publicado no:Cancer
Main Authors: DePeralta, Danielle K., Wei, Lan, Ghoshal, Sarani, Schmidt, Benjamin, Lauwers, Gregory Y., Lanuti, Michael, Chung, Raymond T., Tanabe, Kenneth K., Fuchs, Bryan C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4828262/
https://ncbi.nlm.nih.gov/pubmed/26914713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.29912
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