Performing Permanent Distal Middle Cerebral with Common Carotid Artery Occlusion in Aged Rats to Study Cortical Ischemia with Sustained Disability

Stroke typically occurs in elderly people with a range of comorbidities including carotid (or other arterial) atherosclerosis, high blood pressure, obesity and diabetes. Accordingly, when evaluating therapies for stroke in animals, it is important to select a model with excellent face validity. Isch...

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Detalles Bibliográficos
Publicado en:J Vis Exp
Autores principales: Wayman, Christina, Duricki, Denise A., Roy, Lisa A., Haenzi, Barbara, Tsai, Shi-Yen, Kartje, Gwendolyn, Beech, John S., Cash, Diana, Moon, Lawrence
Formato: Artigo
Lenguaje:Inglês
Publicado: MyJove Corporation 2016
Materias:
Medicine
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4828187/
https://ncbi.nlm.nih.gov/pubmed/26967269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/53106
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