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C. elegans miro-1 Mutation Reduces the Amount of Mitochondria and Extends Life Span
Mitochondria play a critical role in aging, however, the underlying mechanism is not well understood. We found that a mutation disrupting the C. elegans homolog of Miro GTPase (miro-1) extends life span. This phenotype requires simultaneous loss of miro-1 from multiple tissues including muscles and...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4827821/ https://ncbi.nlm.nih.gov/pubmed/27064409 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0153233 |
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