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Bioactive lipid profiling reveals drug target engagement of a soluble epoxide hydrolase inhibitor in a murine model of tobacco smoke exposure

The inflammatory process underlying chronic obstructive pulmonary disease (COPD) may be caused by tobacco smoke (TS) exposure. Previous studies show that epoxyeicosatrienoic acids (EETs) possess promising anti-inflammatory properties, therefore stabilization of EETs and other fatty acid epoxides thr...

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Detalhes bibliográficos
Publicado no:J Metabolomics
Main Authors: Nording, Malin L., Yang, Jun, Hoang, Laura, Zamora, Vanessa, Uyeminami, Dale, Espiritu, Imelda, Pinkerton, Kent E., Hammock, Bruce D., Luria, Ayala
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4827720/
https://ncbi.nlm.nih.gov/pubmed/27076918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7243/2059-0008-1-1
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