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Myristic acid hitchhiking on sigma-1 receptor to fend off neurodegeneration
Neurodegenerative diseases are linked to tauopathy as a result of cyclin dependent kinase 5 (cdk5) binding to its p25 activator instead of its p35 activator and becoming over-activated. The overactive complex stimulates the hyperphosphorylation of tau proteins, leading to neurofibrillary tangles (NF...
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| Publicado no: | Receptors Clin Investig |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4827442/ https://ncbi.nlm.nih.gov/pubmed/27077074 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14800/rci.1114 |
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