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PKM2 Inhibitor Shikonin Suppresses TPA-Induced Mitochondrial Malfunction and Proliferation of Skin Epidermal JB6 Cells
Chemoprevention has been a pivotal and effective strategy during the skin cancer treatment. Using human skin normal and tumor samples, we demonstrated that both the expression and activity levels of pyruvate kinase M2 (PKM2) were higher in skin tumor tissues than normal tissues, suggesting that PKM2...
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| Publicat a: | Mol Carcinog |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4827433/ https://ncbi.nlm.nih.gov/pubmed/23255458 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.21988 |
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