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Poly(ADP-Ribose) Polymerase-1 Regulates the Progression of Autoimmune Nephritis in Males by Inducing Necrotic Cell Death and Modulating Inflammation()

Necrotic lesions and necrotic cell death characterize severe autoimmune nephritides, and contribute to local inflammation and to progression of the disease. Poly(ADP-ribose) polymerase-1 (PARP-1), a DNA repair enzyme, is involved in the induction of necrosis and is a key player in the acute and chro...

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Bibliografski detalji
Izdano u:J Immunol
Glavni autori: Jog, Neelakshi R., Dinnall, Joudy-Ann, Gallucci, Stefania, Madaio, Michael P., Caricchio, Roberto
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4827346/
https://ncbi.nlm.nih.gov/pubmed/19454727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0803565
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