Improvement of Neuroenergetics by Hypertonic Lactate Therapy in Patients with Traumatic Brain Injury Is Dependent on Baseline Cerebral Lactate/Pyruvate Ratio

Energy dysfunction is associated with worse prognosis after traumatic brain injury (TBI). Recent data suggest that hypertonic sodium lactate infusion (HL) improves energy metabolism after TBI. Here, we specifically examined whether the efficacy of HL (3h infusion, 30–40 μmol/kg/min) in improving bra...

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Pubblicato in:J Neurotrauma
Autori principali: Quintard, Hervé, Patet, Camille, Zerlauth, Jean-Baptiste, Suys, Tamarah, Bouzat, Pierre, Pellerin, Luc, Meuli, Reto, Magistretti, Pierre J., Oddo, Mauro
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc. 2016
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4827289/
https://ncbi.nlm.nih.gov/pubmed/26421521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/neu.2015.4057
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