Improvement of Neuroenergetics by Hypertonic Lactate Therapy in Patients with Traumatic Brain Injury Is Dependent on Baseline Cerebral Lactate/Pyruvate Ratio

Energy dysfunction is associated with worse prognosis after traumatic brain injury (TBI). Recent data suggest that hypertonic sodium lactate infusion (HL) improves energy metabolism after TBI. Here, we specifically examined whether the efficacy of HL (3h infusion, 30–40 μmol/kg/min) in improving bra...

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Detalhes bibliográficos
Publicado no:J Neurotrauma
Main Authors: Quintard, Hervé, Patet, Camille, Zerlauth, Jean-Baptiste, Suys, Tamarah, Bouzat, Pierre, Pellerin, Luc, Meuli, Reto, Magistretti, Pierre J., Oddo, Mauro
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2016
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4827289/
https://ncbi.nlm.nih.gov/pubmed/26421521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/neu.2015.4057
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