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Effects of missense mutations in sortase A gene on enzyme activity in Streptococcus mutans

BACKGROUND: Streptococcus mutans (S. mutans) is the major aetiological agent of dental caries, and the transpeptidase Sortase A (SrtA) plays a major role in cariogenicity. The T168G and G470A missense mutations in the srtA gene may be linked to caries susceptibility, as demonstrated in our previous...

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Publicado en:BMC Oral Health
Main Authors: Zhuang, P. L., Yu, L. X., Tao, Y., Zhou, Y., Zhi, Q. H., Lin, H. C.
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4827206/
https://ncbi.nlm.nih.gov/pubmed/27068451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12903-016-0204-1
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