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Sequential signaling crosstalk regulates endomesoderm segregation in sea urchin embryos
Segregation of embryonic endomesoderm into separate endoderm and mesoderm fates is not well understood in deuterostomes. Using sea urchin embryos, we show that Notch signaling initiates segregation of the endomesoderm precursor field by inhibiting expression of a key endoderm transcription factor in...
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| Publicado no: | Science |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4827163/ https://ncbi.nlm.nih.gov/pubmed/22301319 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1212867 |
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