TNF-α enhancement of CD62E mediates adhesion of non–small cell lung cancer cells to brain endothelium via CD15 in lung-brain metastasis

BACKGROUND: CD15, which is overexpressed on various cancers, has been reported as a cell adhesion molecule that plays a key role in non-CNS metastasis. However, the role of CD15 in brain metastasis is largely unexplored. This study provides a better understanding of CD15/CD62E interaction, enhanced...

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發表在:Neuro Oncol
Main Authors: Jassam, Samah A., Maherally, Zaynah, Smith, James R., Ashkan, Keyoumars, Roncaroli, Federico, Fillmore, Helen L., Pilkington, Geoffrey J.
格式: Artigo
語言:Inglês
出版: Oxford University Press 2016
主題:
Basic and Translational Investigations
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4827040/
https://ncbi.nlm.nih.gov/pubmed/26472821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nov248
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