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Genetic Risk Scores Implicated in Adult Bone Fragility Associate With Pediatric Bone Density

Using adult identified bone mineral density (BMD) loci, we calculated genetic risk scores (GRS) to determine if they were associated with changes in BMD during childhood. Longitudinal data from the Bone Mineral Density in Childhood Study were analyzed (N = 798, 54% female, all European ancestry). Pa...

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Detalhes bibliográficos
Publicado no:J Bone Miner Res
Main Authors: Mitchell, Jonathan A, Chesi, Alessandra, Elci, Okan, McCormack, Shana E, Roy, Sani M, Kalkwarf, Heidi J, Lappe, Joan M, Gilsanz, Vicente, Oberfield, Sharon E, Shepherd, John A, Kelly, Andrea, Grant, Struan FA, Zemel, Babette S
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4826827/
https://ncbi.nlm.nih.gov/pubmed/26572781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2744
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