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Parameters Determining the Efficacy of CD32 to Inhibit Activation of FcεRI in Human Basophils

The conditions needed to readily observe the role of CD32 in modulating IgE-mediated secretion are enumerated and include consideration of IgG subclass, with a possible emphasis on IgG3, antibody:antigen ratios, but with no evidence that polymorphic variants of CD32 influence its function.

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Bibliographic Details
Published in:J Allergy Clin Immunol
Main Authors: MacGlashan, Donald, Hamilton, Robert G.
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4826808/
https://ncbi.nlm.nih.gov/pubmed/26774660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2015.10.043
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