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Imaging of Secreted Extracellular Periostin, an Important Marker of Invasion in the Tumor Microenvironment in Esophageal Cancer

Periostin, an extracellular matrix protein, plays key role in cell adhesion and motility within the tumor microenvironment and is correlated with tumor invasion. We developed and characterized a PET tracer that specifically targets periostin and evaluated the probe in preclinical models of esophagea...

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Detalhes bibliográficos
Publicado no:J Nucl Med
Main Authors: Heidari, Pedram, Esfahani, Shadi A., Turker, Nazife S., Wong, Gabrielle, Wang, Timothy C., Rustgi, Anil K., Mahmood, Umar
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4826779/
https://ncbi.nlm.nih.gov/pubmed/26069303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.115.156216
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