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Dlx5 homedomain/DNA complex; Structure, binding and effect of mutations related to split-hand and foot malformation syndrome

The Dlx5 homeodomain is a transcription factor related to the Drosophila Distal-less gene that is associated with breast and lung cancer, lymphoma, Rett syndrome and osteoporosis in humans. Mutations in the DLX5 gene have been linked to deficiencies in craniofacial and limb development in higher euk...

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Publicado en:J Mol Biol
Autores principales: Proudfoot, Andrew, Axelrod, Herbert L., Geralt, Michael, Fletterick, Robert J, Yumoto, Fumiaki, Deacon, Ashley M., Elsliger, Marc-André, Wilson, Ian A., Wüthrich, Kurt, Serrano, Pedro
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4826628/
https://ncbi.nlm.nih.gov/pubmed/26829219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2016.01.023
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