Dlx5 homedomain/DNA complex; Structure, binding and effect of mutations related to split-hand and foot malformation syndrome

The Dlx5 homeodomain is a transcription factor related to the Drosophila Distal-less gene that is associated with breast and lung cancer, lymphoma, Rett syndrome and osteoporosis in humans. Mutations in the DLX5 gene have been linked to deficiencies in craniofacial and limb development in higher euk...

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Vydáno v:J Mol Biol
Hlavní autoři: Proudfoot, Andrew, Axelrod, Herbert L., Geralt, Michael, Fletterick, Robert J, Yumoto, Fumiaki, Deacon, Ashley M., Elsliger, Marc-André, Wilson, Ian A., Wüthrich, Kurt, Serrano, Pedro
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4826628/
https://ncbi.nlm.nih.gov/pubmed/26829219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2016.01.023
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