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CollapsABEL: an R library for detecting compound heterozygote alleles in genome-wide association studies

BACKGROUND: Compound Heterozygosity (CH) in classical genetics is the presence of two different recessive mutations at a particular gene locus. A relaxed form of CH alleles may account for an essential proportion of the missing heritability, i.e. heritability of phenotypes so far not accounted for b...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Zhong, Kaiyin, Karssen, Lennart C., Kayser, Manfred, Liu, Fan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4826552/
https://ncbi.nlm.nih.gov/pubmed/27059780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-016-1006-9
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