Lipoxin A4 inhibits microglial activation and reduces neuroinflammation and neuropathic pain after spinal cord hemisection

BACKGROUND: Spinal cord injury (SCI) is a severe neurological disorder with many disabling consequences, including persistent neuropathic pain, which develops in about 40 % of SCI patients and is induced and sustained by excessive and uncontrolled spinal neuroinflammation. Here, we have evaluated th...

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Détails bibliographiques
Publié dans:J Neuroinflammation
Auteurs principaux: Martini, Alessandra Cadete, Berta, Temugin, Forner, Stefânia, Chen, Gang, Bento, Allisson Freire, Ji, Ru-Rong, Rae, Giles Alexander
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2016
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Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4826542/
https://ncbi.nlm.nih.gov/pubmed/27059991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0540-8
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