Suppression of Enhancer Overactivation by a RACK7-Histone Demethylase Complex

Regulation of enhancer activity is important for controlling gene expression programs. Here we report that a biochemical complex that contains a potential chromatin reader, RACK7 and the histone lysine 4 tri-methyl (H3K4me3)-specific demethylase KDM5C occupies many active enhancers, including almost...

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Publicat a:Cell
Autors principals: Shen, Hongjie, Xu, Wenqi, Guo, Rui, Rong, Bowen, Gu, Lei, Wang, Zhentian, He, Chenxi, Zheng, Lijuan, Hu, Xin, Hu, Zhen, Shao, Zhi-Ming, Yang, Pengyuan, Wu, Feizhen, Shi, Yujiang Geno, Shi, Yang, Lan, Fei
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4826479/
https://ncbi.nlm.nih.gov/pubmed/27058665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.02.064
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