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Distinct roles of autophagy-dependent and -independent functions of FIP200 revealed by generation and analysis of a mutant knock-in mouse model

Autophagy is an evolutionarily conserved cellular process controlled through a set of essential autophagy genes (Atgs). However, there is increasing evidence that most, if not all, Atgs also possess functions independent of their requirement in canonical autophagy, making it difficult to distinguish...

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Bibliografske podrobnosti
izdano v:Genes Dev
Main Authors: Chen, Song, Wang, Chenran, Yeo, Syn, Liang, Chun-Chi, Okamoto, Takako, Sun, Shaogang, Wen, Jian, Guan, Jun-Lin
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4826400/
https://ncbi.nlm.nih.gov/pubmed/27013233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.276428.115
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