Distinct roles of autophagy-dependent and -independent functions of FIP200 revealed by generation and analysis of a mutant knock-in mouse model

Autophagy is an evolutionarily conserved cellular process controlled through a set of essential autophagy genes (Atgs). However, there is increasing evidence that most, if not all, Atgs also possess functions independent of their requirement in canonical autophagy, making it difficult to distinguish...

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Bibliographic Details
Published in:Genes Dev
Main Authors: Chen, Song, Wang, Chenran, Yeo, Syn, Liang, Chun-Chi, Okamoto, Takako, Sun, Shaogang, Wen, Jian, Guan, Jun-Lin
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2016
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4826400/
https://ncbi.nlm.nih.gov/pubmed/27013233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.276428.115
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