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Mammalian Heat Shock Response And Mechanisms Underlying Its Genome-wide Transcriptional Regulation

The Heat Shock Response (HSR) is critical for survival of all organisms. However, it’s scope, extent, and the molecular mechanism of regulation is poorly understood. Here we show the genome-wide transcriptional response to heat-shock in mammals is rapid, dynamic, and results in induction of several...

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Publicado en:Mol Cell
Main Authors: Mahat, Dig B., Salamanca, H. Hans, Duarte, Fabiana M., Danko, Charles G., Lis, John T.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4826300/
https://ncbi.nlm.nih.gov/pubmed/27052732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.02.025
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