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Mammalian Heat Shock Response And Mechanisms Underlying Its Genome-wide Transcriptional Regulation

The Heat Shock Response (HSR) is critical for survival of all organisms. However, it’s scope, extent, and the molecular mechanism of regulation is poorly understood. Here we show the genome-wide transcriptional response to heat-shock in mammals is rapid, dynamic, and results in induction of several...

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Pubblicato in:Mol Cell
Autori principali: Mahat, Dig B., Salamanca, H. Hans, Duarte, Fabiana M., Danko, Charles G., Lis, John T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4826300/
https://ncbi.nlm.nih.gov/pubmed/27052732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.02.025
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