miR-101 reverses hypomethylation of the PRDM16 promoter to disrupt mitochondrial function in astrocytoma cells

Our previous report identified PR domain containing 16 (PRDM16), a member of the PR-domain gene family, as a new methylation associated gene in astrocytoma cells. This previous study also reported that miR-101 is a tumor suppressor in glioma. The present study confirms that PRDM16 is a hypomethylate...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Lei, Qianqian, Liu, Xiaoping, Fu, Haijuan, Sun, Yingnan, Wang, Liping, Xu, Gang, Wang, Wei, Yu, Zhibin, Liu, Changhong, Li, Peiyao, Feng, Jianbo, Li, Guiyuan, Wu, Minghua
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4826261/
https://ncbi.nlm.nih.gov/pubmed/26701852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6652
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