Deep sequencing of uveal melanoma identifies a recurrent mutation in PLCB4

Next generation sequencing of uveal melanoma (UM) samples has identified a number of recurrent oncogenic or loss-of-function mutations in key driver genes including: GNAQ, GNA11, EIF1AX, SF3B1 and BAP1. To search for additional driver mutations in this tumor type we carried out whole-genome or whole...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Johansson, Peter, Aoude, Lauren G., Wadt, Karin, Glasson, William J., Warrier, Sunil K., Hewitt, Alex W., Kiilgaard, Jens Folke, Heegaard, Steffen, Isaacs, Tim, Franchina, Maria, Ingvar, Christian, Vermeulen, Tersia, Whitehead, Kevin J., Schmidt, Christopher W., Palmer, Jane M., Symmons, Judith, Gerdes, Anne-Marie, Jönsson, Göran, Hayward, Nicholas K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2015
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4826231/
https://ncbi.nlm.nih.gov/pubmed/26683228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6614
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