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Induction of MAPK- and ROS-dependent autophagy and apoptosis in gastric carcinoma by combination of romidepsin and bortezomib

Proteasome inhibitors and histone deacetylase (HDAC) inhibitors can synergistically induce apoptotic cell death in certain cancer cell types but their combinatorial effect on the induction of autophagy remains unknown. Here, we investigated the combinatorial effects of a proteasome inhibitor, bortez...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Oncotarget
Päätekijät: Hui, Kwai Fung, Yeung, Po Ling, Chiang, Alan K.S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Impact Journals LLC 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4826218/
https://ncbi.nlm.nih.gov/pubmed/26683357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6601
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