Epigenetic modification of TLR4 promotes activation of NF-κB by regulating methyl-CpG-binding domain protein 2 and Sp1 in gastric cancer

Toll-like receptor 4 (TLR4) is important in promoting the immune response in various cancers. Recently, TLR4 is highly expressed in a stage-dependent manner in gastric cancer, but the regulatory mechanism of TLR4 expression has been not elucidated it. Here, we investigated the mechanism underlying r...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Kim, Tae Woo, Lee, Seon-Jin, Oh, Byung Moo, Lee, Heesoo, Uhm, Tae Gi, Min, Jeong-Ki, Park, Young-Jun, Yoon, Suk Ran, Kim, Bo-Yeon, Kim, Jong Wan, Choe, Yong-Kyung, Lee, Hee Gu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2015
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4826199/
https://ncbi.nlm.nih.gov/pubmed/26675260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6549
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