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PUMA: a puzzle piece in chloroquine’s antimelanoma activity
Chloroquine can induce cell death in a subset of cancer cell lines, and some melanoma cell lines are quite susceptible. While it is well known that chloroquine impairs lysosomal function and can serve as an autophagy inhibitor, the molecular target of chloroquine and the subsequent cascade of events...
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| Publicado no: | J Invest Dermatol |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4825873/ https://ncbi.nlm.nih.gov/pubmed/23949767 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2013.135 |
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