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Punctate LC3B expression is a common feature of solid tumors and associated with proliferation, metastasis and poor outcome

PURPOSE: Measurement of autophagy in cancer and correlation with histopathologic grading or clinical outcomes has been limited. Accordingly, we investigated LC3B as an autophagosome marker by analyzing nearly 1400 tumors from 20 types of cancer, focussing on correlations with clinical outcomes in me...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Lazova, Rossitza, Camp, Robert L., Klump, Vincent, Siddiqui, Summar F., Amaravadi, Ravi K., Pawelek, John M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4825867/
https://ncbi.nlm.nih.gov/pubmed/22080440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-1282
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