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Calpain restrains the stem cells compartment in breast cancer
CAPNS1 is essential for the stability and function of ubiquitous CAPN1 and CAPN2. Calpain modulates by proteolytic cleavage many cellular substrates and its activity is often deregulated in cancer cells, therefore calpain inhibition has been proposed as a therapeutical strategy for a number of malig...
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Publicado no: | Cell Cycle |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Taylor & Francis
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4825769/ https://ncbi.nlm.nih.gov/pubmed/26771715 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1121325 |
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