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Calpain restrains the stem cells compartment in breast cancer

CAPNS1 is essential for the stability and function of ubiquitous CAPN1 and CAPN2. Calpain modulates by proteolytic cleavage many cellular substrates and its activity is often deregulated in cancer cells, therefore calpain inhibition has been proposed as a therapeutical strategy for a number of malig...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Raimondi, M., Marcassa, E., Cataldo, F., Arnandis, T., Mendoza-Maldonado, R., Bestagno, M., Schneider, C., Demarchi, F.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4825769/
https://ncbi.nlm.nih.gov/pubmed/26771715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1121325
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