Rap1 induces cytokine production in pro-inflammatory macrophages through NFκB signaling and is highly expressed in human atherosclerotic lesions

Repressor activator protein 1 (Rap1) is essential for maintaining telomere length and structural integrity, but it also exerts other non-telomeric functions. The present study tested the hypothesis that Rap1 is released into the cytoplasm and induces production of pro-inflammatory cytokines via nucl...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Cai, Yin, Sukhova, Galina K, Wong, Hoi Kin, Xu, Aimin, Tergaonkar, Vinay, Vanhoutte, Paul M, Tang, Eva Hoi Ching
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
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Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4825742/
https://ncbi.nlm.nih.gov/pubmed/26505215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1100771
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