Rev7/Mad2B plays a critical role in the assembly of a functional mitotic spindle

The spindle assembly checkpoint (SAC) acts as a guardian against cellular threats that may lead to chromosomal missegregation and aneuploidy. Mad2, an anaphase-promoting complex/cyclosome-Cdc20 (APC/C(Cdc20)) inhibitor, has an additional homolog in mammals known as Mad2B, Mad2L2 or Rev7. Apart from...

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Bibliografske podrobnosti
izdano v:Cell Cycle
Main Authors: Bhat, Audesh, Wu, Zhaojia, Maher, Veronica M, McCormick, J Justin, Xiao, Wei
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2015
Teme:
Report
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4825701/
https://ncbi.nlm.nih.gov/pubmed/26697843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1120922
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