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Glutamine contributes to maintenance of mouse embryonic stem cell self-renewal through PKC-dependent downregulation of HDAC1 and DNMT1/3a

Although glutamine (Gln) is not an essential amino acid, it is considered a critical substrate in many key metabolic processes that control a variety of physiological functions and are involved in regulating early embryonic development. Thus, we investigated the effect of Gln on regulation of mouse...

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Pubblicato in:Cell Cycle
Autori principali: Ryu, Jung Min, Lee, Sang Hun, Seong, Je Kyung, Han, Ho Jae
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4825587/
https://ncbi.nlm.nih.gov/pubmed/26375799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1087620
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