Gene-expression and in vitro function of mesenchymal stromal cells are affected in juvenile myelomonocytic leukemia

An aberrant interaction between hematopoietic stem cells and mesenchymal stromal cells has been linked to disease and shown to contribute to the pathophysiology of hematologic malignancies in murine models. Juvenile myelomonocytic leukemia is an aggressive malignant disease affecting young infants....

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Foilsithe in:Haematologica
Main Authors: Calkoen, Friso G.J., Vervat, Carly, Eising, Else, Vijfhuizen, Lisanne S., ‘t Hoen, Peter-Bram A.C., van den Heuvel-Eibrink, Marry M., Egeler, R. Maarten, van Tol, Maarten J.D., Ball, Lynne M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Ferrata Storti Foundation 2015
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4825298/
https://ncbi.nlm.nih.gov/pubmed/26294732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2015.126938
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