Epitope analysis and protection by a ROP19 DNA vaccine against Toxoplasma gondii

We used bioinformatics approaches to identify B-cell and T-cell epitopes on the ROP19 protein of Toxoplasma gondii. Then, we constructed plasmids with ROP19 (pEGFP-C1-ROP19) and injected them into BALB/c mice to test the immunoprotection induced by this vaccine candidate. The results showed that imm...

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Dettagli Bibliografici
Pubblicato in:Parasite
Autori principali: Zhou, Jian, Wang, Lin, Lu, Gang, Zhou, Aihua, Zhu, Meiyan, Li, Qihang, Wang, Zhilin, Arken, Miradel, Wang, Ao, He, Shenyi
Natura: Artigo
Lingua:Inglês
Pubblicazione: EDP Sciences 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4824872/
https://ncbi.nlm.nih.gov/pubmed/27055564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1051/parasite/2016017
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