Oncolytic vesicular stomatitis virus expressing interferon-γ has enhanced therapeutic activity

Oncolytic viruses are known to stimulate the antitumor immune response by specifically replicating in tumor cells. This is believed to be an important aspect of the durable responses observed in some patients and the field is rapidly moving toward immunotherapy. As a further means to engage the immu...

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Pubblicato in:Mol Ther Oncolytics
Autori principali: Bourgeois-Daigneault, Marie-Claude, Roy, Dominic Guy, Falls, Theresa, Twumasi-Boateng, Kwame, St-Germain, Lauren Elizabeth, Marguerie, Monique, Garcia, Vanessa, Selman, Mohammed, Jennings, Victoria Ann, Pettigrew, Jessica, Amos, Sally, Diallo, Jean-Simon, Nelson, Brad, Bell, John Cameron
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4824565/
https://ncbi.nlm.nih.gov/pubmed/27119116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mto.2016.1
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