Deceased-Donor Apolipoprotein L1 Renal-Risk Variants Have Minimal Effects on Liver Transplant Outcomes

BACKGROUND: Apolipoprotein L1 gene (APOL1) G1 and G2 renal-risk variants, common in populations with recent African ancestry, are strongly associated with non-diabetic nephropathy, end-stage kidney disease, and shorter allograft survival in deceased-donor kidneys (autosomal recessive inheritance). C...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Dorr, Casey R., Freedman, Barry I., Hicks, Pamela J., Brown, W. Mark, Russell, Gregory B., Julian, Bruce A., Pastan, Stephen O., Gautreaux, Michael D., Muthusamy, Amutha, Chinnakotla, Srinath, Hauptfeld, Vera, Bray, Robert A., Kirk, Allan D., Divers, Jasmin, Israni, Ajay K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4824450/
https://ncbi.nlm.nih.gov/pubmed/27054572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0152775
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