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Granzyme A Is Expressed in Mouse Lungs during Mycobacterium tuberculosis Infection but Does Not Contribute to Protection In Vivo

Granzyme A, a serine protease expressed in the granules of cytotoxic T and Natural Killer cells, is involved in the generation of pro-inflammatory cytokines by macrophages. Granzyme A has been described to induce in macrophages in vitro the activation of pro-inflammatory pathways that impair intrace...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Uranga, Santiago, Marinova, Dessislava, Martin, Carlos, Pardo, Julián, Aguilo, Nacho
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4824395/
https://ncbi.nlm.nih.gov/pubmed/27055232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0153028
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