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Development of Type 2, But Not Type 1, Leprosy Reactions is Associated with a Severe Reduction of Circulating and In situ Regulatory T-Cells

Leprosy is frequently complicated by the appearance of reactions that are difficult to treat and are the main cause of sequelae. We speculated that disturbances in regulatory T-cells (Tregs) could play a role in leprosy reactions. We determined the frequency of circulating Tregs in patients with typ...

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Podrobná bibliografie
Vydáno v:Am J Trop Med Hyg
Hlavní autoři: Vieira, Ana Paula, Trindade, Maria Ângela Bianconcini, Pagliari, Carla, Avancini, João, Sakai-Valente, Neusa Yurico, Duarte, Alberto José da Silva, Benard, Gil
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society of Tropical Medicine and Hygiene 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4824210/
https://ncbi.nlm.nih.gov/pubmed/26903606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4269/ajtmh.15-0673
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