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Antenatal BAY 41-2272 reduces pulmonary hypertension in the rabbit model of congenital diaphragmatic hernia

Infants with congenital diaphragmatic hernia (CDH) fail to adapt at birth because of persistent pulmonary hypertension (PH), a condition characterized by excessive muscularization and abnormal vasoreactivity of pulmonary vessels. Activation of soluble guanylate cyclase by BAY 41-2272 prevents pulmon...

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Detalhes bibliográficos
Publicado no:Am J Physiol Lung Cell Mol Physiol
Main Authors: Vuckovic, Aline, Herber-Jonat, Susanne, Flemmer, Andreas W., Strizek, Brigitte, Engels, Alexander C., Jani, Jacques C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4824165/
https://ncbi.nlm.nih.gov/pubmed/26873974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00178.2015
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