Solution structure of the Z-DNA binding domain of PKR-like protein kinase from Carassius auratus and quantitative analyses of the intermediate complex during B–Z transition

Z-DNA binding proteins (ZBPs) play important roles in RNA editing, innate immune response and viral infection. Structural and biophysical studies show that ZBPs initially form an intermediate complex with B-DNA for B–Z conversion. However, a comprehensive understanding of the mechanism of Z-DNA bind...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Lee, Ae-Ree, Park, Chin-Ju, Cheong, Hae-Kap, Ryu, Kyoung-Seok, Park, Jin-Wan, Kwon, Mun-Young, Lee, Janghyun, Kim, Kyeong Kyu, Choi, Byong-Seok, Lee, Joon-Hwa
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2016
Témata:
Structural Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4824103/
https://ncbi.nlm.nih.gov/pubmed/26792893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw025
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