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Synthetic dual-input mammalian genetic circuits enable tunable and stringent transcription control by chemical and light

Programmable transcription factors can enable precise control of gene expression triggered by a chemical inducer or light. To obtain versatile transgene system with combined benefits of a chemical inducer and light inducer, we created various chimeric promoters through the assembly of different copi...

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Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Chen, Xianjun, Li, Ting, Wang, Xue, Du, Zengmin, Liu, Renmei, Yang, Yi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4824083/
https://ncbi.nlm.nih.gov/pubmed/26673714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1343
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