Downregulation of renal tubular Wnt/β-catenin signaling by Dickkopf-3 induces tubular cell death in proteinuric nephropathy

Studies on the role of Wnt/β-catenin signaling in different forms of kidney disease have yielded discrepant results. Here, we report the biphasic change of renal β-catenin expression in mice with overload proteinuria in which β-catenin was upregulated at the early stage (4 weeks after disease induct...

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Библиографические подробности
Опубликовано в: :Cell Death Dis
Главные авторы: Wong, D W L, Yiu, W H, Wu, H J, Li, R X, Liu, Y, Chan, K W, Leung, J C K, Chan, L Y Y, Lai, K N, Tang, S C W
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2016
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Original Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4823961/
https://ncbi.nlm.nih.gov/pubmed/27010856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.62
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