IL10 inhibits starvation-induced autophagy in hypertrophic scar fibroblasts via cross talk between the IL10-IL10R-STAT3 and IL10-AKT-mTOR pathways

Hypertrophic scar (HS) is a serious skin fibrotic disease characterized by excessive hypercellularity and extracellular matrix (ECM) component deposition. Autophagy is a tightly regulated physiological process essential for cellular maintenance, differentiation, development, and homeostasis. Previou...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Shi, J, Wang, H, Guan, H, Shi, S, Li, Y, Wu, X, Li, N, Yang, C, Bai, X, Cai, W, Yang, F, Wang, X, Su, L, Zheng, Z, Hu, D
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4823945/
https://ncbi.nlm.nih.gov/pubmed/26962683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.44
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