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Knockout of Atg5 delays the maturation and reduces the survival of adult-generated neurons in the hippocampus
Autophagy is an evolutionarily conserved lysosomal degradation pathway that plays important roles in cell maintenance, expansion and differentiation. Removal of genes essential for autophagy from embryonic neural stem and precursor cells reduces the survival and inhibits neuronal differentiation of...
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| Publicat a: | Cell Death Dis |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4823925/ https://ncbi.nlm.nih.gov/pubmed/26938300 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.406 |
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