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Characterizing heterogeneity in the response of synovial mesenchymal progenitor cells to synovial macrophages in normal individuals and patients with osteoarthritis

BACKGROUND: Resident macrophages in OA synovial tissue contribute to synovitis through pro-inflammatory mediators driving cartilage loss. What remains unknown is how these macrophages interact with synovial mesenchymal progenitor cells (sMPCs) in the joint. sMPCs have the potential to undergo chondr...

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Detalhes bibliográficos
Publicado no:J Inflamm (Lond)
Main Authors: Fichadiya, Akash, Bertram, Karri L, Ren, Guomin, Yates, Robin M, Krawetz, Roman J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4823907/
https://ncbi.nlm.nih.gov/pubmed/27057150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12950-016-0120-9
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